Low Dose Naltrexone VS. Your Polymorphysm

Raising Awareness, One Doctor At A Time

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Low Dose Naltrexone VS.
Your Polymorphysm

A quote from our facebook page by the founder, Sterling Hill:

“For all of my LDN people out there. People with the G allele for OPRM1 rs1799971 have a better outcome when using naltrexone than people with the A allele. This study was done on naltrexone and not the low dose. Here is what 23andme states:

As part of a much larger study, researchers studied the effect of genetics on naltrexone effectiveness in treating alcohol dependence by comparing 146 patients who received naltrexone to 161 who received a placebo. All 307 patients also received counseling about adherence to their medication plans. The researchers found that SNP rs1799971 in the OPRM1 gene influenced the likelihood that a person taking naltrexone would have a “good clinical outcome,” which was defined by either abstinence or moderate drinking without problems.

Patients with a G at one or both copies of rs1799971 were more than five times as likely to have a good clinical outcome compared to those with the AA genotype.”

Sterling Hill, CEO of MTHFR Support

Are you interested in finding out your OPRM1 status? Then head over to
MTHFR Support and check out Sterling’s App!

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By |2023-01-22T16:54:52-06:00August 4th, 2021|Education, Feature, Genetics, Health, Sterling's App|Comments Off on Low Dose Naltrexone VS. Your Polymorphysm

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