CBS upregulation an ammonia ur (BUN)

[christian.penninckParticipant October 21, 2016 at 4:47 pm Post count: 4]

#35602

Hi ,
I have CBS C699T AG +- Hetero , CBS N212N AG +- Hetero
As I understood this can cause to much ammonia.
Unfortunately here in Belgium MD’s are only willing to do ammonia testing if you have a Hepatic problem.
So I have problems having my ammonia tested.
My question can give my (BUN) blood urea nitrogen me a clue.
Should it read high because much ammonia is produced and thus turned into BUN.
OR can my (BUN) be low-normal bacause the ammonia is not well enough converted to (BUN) because of the SNP’s.
Thanks for advice.

[Lea (Admin)Keymaster October 22, 2016 at 5:21 am Post count: 296]

#35612

Hi Christian,

Your question has been forwarded for reply. We appreciate your patience awaiting a response.

Thank you

Kind Regards
Lea

[christian.penninckParticipant October 22, 2016 at 9:59 am Post count: 4]

#35623

Oeps made a mistake
I see now CBS N212N says not genotyped.
But CBS A360A AG hetero.
Does that change anything??
rs2851391 CBS A13637G CT +/-
rs1801181 CBS A360A AG +/-
rs706209 CBS C*351T AG +/-
rs4920037 CBS C19150T AG +/-
rs234706 CBS C699T AG +/-
rs12613 CBS G*299A CC -/-
rs706208 CBS T*330C AG +/-
? is C699T AG +- an ammonia issue at all or is it only C699T AA ++ ?

[Cynthia SmithParticipant October 22, 2016 at 11:44 pm Post count: 206]

#35645

Hi Christian, Its difficult to discern you ammonia status from SNPs and BUN only. If I were you, I would consider a B multi like Starter B (MTHFRproducts), augmented with Black Bear Energy spray a few weeks later, and the layer in 400 mcgs of 5MTHF after a few weeks after that. I don’t know your SOD2 or Arginine status, but that’s in play as well. Cynthia

[Author]

Posts