What does just a '+' or just a 'minus' mean?

[davidleviParticipant July 16, 2015 at 11:32 am Post count: 5]

#17601

What does it mean when there is just a + or – for a specific gene rather than a +/+, -/-, or +/-? (view attached screen shot)

Screen Capture

[Lea (Admin)Keymaster July 16, 2015 at 8:55 pm Post count: 296]

#17626

Hi David,

I need permission to access the screen capture to be able to assist you with your question. I have sent a request just awaiting your acceptance.

Lea

[Lea (Admin)Keymaster July 16, 2015 at 9:52 pm Post count: 296]

#17629

Hi David,

Thank you I have access to the screen shot now and will share with one of the practitioners who does interpretations. Your patience in awaiting a response
is appreciated. The practitioners respond voluntarily and have their own practices and other commitments so may not be able to respond immediately but do their best.

Lea

[Lea (Admin)Keymaster July 17, 2015 at 12:42 am Post count: 296]

#17635

Hi David,

Could you please provide a screen shot of the COMT SNPs from the same report.

Thank you

Lea

[davidleviParticipant July 20, 2015 at 2:10 pm Post count: 5]

#17772

Any particular part of the COMT SNPs? Because there are about 3 pages of them.

[Lea (Admin)Keymaster July 20, 2015 at 5:55 pm Post count: 296]

#17785

Hi David,

Your post has been forwarded on to the practitioner assisting with your question.

Lea

• This reply was modified 8 years, 9 months ago by  Lea (Admin).

[Cynthia SmithParticipant July 20, 2015 at 7:34 pm Post count: 206]

#17796

Hi Nick,
Reed means two risk alleles, yellow means one risk allele, and green is the expected alleles. In the case of COMT H68H, and V158M, they are down regulations slow down breakdown of catecholamines. If MAOB includes risk alleles, it further slows down COMT enzymatic activity. There are 2 drawing associated with you Variant Report that show COMT. Cynthia

[davidleviParticipant July 21, 2015 at 2:49 pm Post count: 5]

#17837

So a single ‘+’ means the same as a ‘+/+’?

[Lea (Admin)Keymaster July 22, 2015 at 4:11 am Post count: 296]

#17868

Hi David,

Your question has been forwarded.

Lea

[Lea (Admin)Keymaster July 22, 2015 at 4:11 am Post count: 296]

#17869

Hi David,

Your question has been forwarded.

Lea

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