Home Forums MTHFR Support Forum Pregnancy Homozyous C667T and A1298C and trying to get pregnant – Help

Viewing 6 posts - 1 through 6 (of 6 total)
  • Author
    Posts
  • claire.crew
    Participant
    Post count: 1

    Hi I have been trying to get pregnant for 5 years or so and having been through three IVF’s which failed I decided last year to see a nutritionist. The nutritionist looked at my blood test results from the doctor and said she thought I had a problem with Vitamin B12 and Folate so suggested the MTHFR test which we done and came back saying I have homozygous C667T and A1298C. I was put on 400mg of folate twice a day, Vitamin B12 1000mg, Cod Liver Oil, Pre-natal vitamins and a daily probiotic. I’ve recently had a repeat of the blood tests and they are slightly improving but my red blood cells are still a bit large and my iron is still quite low (54) so she has increased my iron tablets to two a day every day. I am also taking baby aspirin daily. I have been to the doctors about this but they have never heard of it and have reluctantly sent a letter to the genetics department at our local hospital but only for advice not for an actual appointment. Any help or tips would be greatly received.

    Thanks

    Lea (Admin)
    Keymaster
    Post count: 296

    Hi Claire,

    There are many practitioners now who do know about this and can advise you. Please consider doing 23andMe and running your raw data through Sterling’s App and consulting with one of the practitioners on the Find A Practitioner listing here https://mthfrsupport.com/find-a-practitioner/.
    Many will consult via Skype or phone. They will be able to interpret your results and provide advice and treatment specific to your needs.

    Lea

    dillonlisa1
    Participant
    Post count: 2

    I’m homozygous and have had 10+ miscarriages. I didn’t realise how bad synthetic folic acid was for me, didn’t realise how important the word ‘active’ is in relation to folate and vit B.

    Make sure all your supplements are active.

    I’ve started writing a blog on it, including photos of the supplements I’m now taking:
    http://recurrentmiscarriage2.blogspot.co.nz/2015/05/mthfr-gene-mutation-and-folic-acid-is.html

    Lea (Admin)
    Keymaster
    Post count: 296

    Hi dillionlisa1,

    I have forwarded your post for reply. Your patience in awaiting a response is appreciated.

    Lea

    Cynthia Smith
    Participant
    Post count: 206

    Hi dillonlisa1,

    I noticed that you mentioned that your RBC’s are a “bit large”. This would be your MCV.
    A little background….Folate and B12 undergo a methyl swap inside the cells in order to participate in “methylation,” but the B12 and folate have to get into the cells. In order to get into the cells, carrier proteins are need to ferry them. The carrier proteins are determined by our genetics. SO, for example, B12 carrier proteins are, inter alia, TCN 1 and 2 and GIF. Typically are larger MCV number indicates a problem in the B12 transport system (or vegetarian). Because you are taking B12 and folate, you may want to consider pulsing lithium orate a few times per week, as it is the carrier protein’s nutrient cofactor. Many folks are low in the mineral lithium. Seeking Health sells it.
    Also, good cell membrane health is important. Sometime a bit of sunflower lecithin liquid is helpful in providing cells membrane building blocks (phosphor-lipids).
    Also, if you have SNPs in MTHFS, you may want to avoid FOLINIC acid in your Prenatal. Cynthia

    Dr Jacquie
    Participant
    Post count: 9

    Hi Lisa,

    It would be safer and more successful for you if you consulted with a trained naturopathic physician rather than trying bits and pieces of recommendations from blogs. Pregnancy is a delicate issue and deserves a comprehensive approach. I am licensed in Arizona as a naturopathic physician and have received advanced training in Chinese herbal medicine and stay current with a Chinese mentor. I work internationally with my patients by Skype. For more information you can find me on http://greenfieldsclinic.co.uk or reply here.

Viewing 6 posts - 1 through 6 (of 6 total)
  • The forum ‘Pregnancy’ is closed to new topics and replies.