Compound Heterozygous RPL – Preparing for Health PregnancyCompound Heterozygo

[msz1191Participant October 29, 2013 at 7:28 pm Post count: 3]

#2701

I was recently diagnosed as being compound heterozygous (A1298 and C677T) after suffering my second misccariage. My doctor has told me this was not an issue since my homocysteine levels are normal. I was prescribed with a Rx folic and B vitamin compound (Foltx), but do not feel that I will be addressing this issue by taking it. I have shown the doctor articles from this site, and have been dismissed each time stating that all studies she is famililar with indicate that MTHFR is not a cause for miscarriages. I am deciding to take matters into my own hands and purchase the supplements OTC. I just bought Thorne prenatal and a bunch of Solgar products and a local health foods store. However, I am so confused how much to take! The Thorne Prenatal contains 1000mcg Folate (500 mcg as Calcium Folate and 500mcg as L-5-Methyltetrahydrofolate, 200 mcg B12 (100 mcg as Adenosycolbalamin and 100 mcg Methylcobalamin, and 10mg B6 (as P-5-P). I also purchased the following Solgar products: 1000mcg Folate, 1000mcb Methylcobalamin, and 50mg P-5-P. I read the articles that stated that too much Methylfolate could product some adverse symptoms and to start slowly. Is the Thorne prenatal enough to start? Or should I add in some of the Solgar products as well? Please help! This is all so confusing to me! I really want to prepare my body to sustain a healthy pregnancy! Hopefully pregnancy #3 will stick!
I also wanted to note that I went through VERY comprehensive testing with a fertility specialist, and nothing was found besides the MTHFR mutations. My hormone levels looked good, anatomy of cervix/fallopian tubes healthy, no other genetic anamolies.

[Sterling Hill ErdeiKeymaster November 7, 2013 at 7:44 am Post count: 123]

#2776

Folate deficiency can be serious!
If you are folate deficient, your red blood cells can become misshapen with hooks on them. The uterus is fed by capillaries. And BAM! there is miscarriage. Does not take rocket science for this one. Hopefully your doctor understands this and changes his or her mind.
To get a practitioner to actually know what they are doing, we have a list started under find a practitioner.

If not you can go to your doctor and see if he will test for homocysteine and tell you that number and not just tell you the words it is in range because most are clueless.

And if you are eating foods fortified with folic acid, you might want to consider a whole serum folic acid panel. If you have been eating your cheerios, bread, flour, rice, etc.. loaded with synthetic folic acid and your folic acid level come back crazy high you will know that MTHFR is expressing because we cannot convert unmetabolized folic acid into the active bio available form of folate. And unmetabolized folic acid is one of the leading causes of renal failure and colon cancer. Some countries have realized this and have stopped fortification. Because many have MTHFR expression.

Also if your T Cells are low MTHFR could be expressing since it causes poor t cell regulation.

Also a whole serum FOLATE not folic. And if the folate test comes back low you will know MTHFR is expressing.

Also a doctor can put your red blood cells under a microscope and if your rbc’s are misshapen with hooks on them this is also a sign of poor diet and MTHFR.

Sterling

[IstvanParticipant December 1, 2013 at 9:26 am Post count: 136]

#2945

Test

[Sterling Hill ErdeiKeymaster December 1, 2013 at 9:17 pm Post count: 123]

#2950

Hello

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