We’ve again updated and expanded our COVID-19 report and Gene/SNP guide! This time we focused on G6PD and more than tripled the number of secondary SNPs we’re looking at. Iron upregulation is happening to many who get COVID-19. G6PD SNPs are categorized into Class I, II and III as the WHO classifies them.
Class I: Severe deficiency (<10% activity) with chronic (nonspherocytic) hemolytic anemia
Class II: Severe deficiency (<10% activity), with intermittent hemolysis
Class III: Mild deficiency (10-60% activity), hemolysis with stressors only